I've had Lyme's Disease, but not chronic Lyme's. I was treated right away, recovered fully, and will be forever grateful for that. Lyme's is very common in this area and everybody is always talking about it. I've heard people say that they do better on a no sugar/no wheat diet - that the spirochetes thrive in a high blood sugar environment. Or maybe it's because the immune system works better without sugar in the diet. I don't know, but I think you're on the right track with W30 and I wish you the best.